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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PSMC5 All Species: 33.33
Human Site: Y24 Identified Species: 56.41
UniProt: P62195 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P62195 NP_002796.4 406 45626 Y24 G S G L R Q Y Y L S K I E E L
Chimpanzee Pan troglodytes XP_001149845 406 45725 Y24 G S G L R Q Y Y L S K I E E L
Rhesus Macaque Macaca mulatta XP_001108909 477 53189 Y95 G S G L R Q Y Y L S K I E E L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus P46471 433 48629 Q38 A L L K T Y G Q S T Y S R Q I
Rat Rattus norvegicus P62193 440 49166 K64 Q C R L K L L K L E R I K D Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus Q90732 440 49185 K64 Q C R L K L L K L E R I K D Y
Frog Xenopus laevis P46470 461 52229 Y19 G T G L R Q Y Y L S K I E D L
Zebra Danio Brachydanio rerio NP_001003740 406 45613 Y24 G S G L R Q Y Y L S K I E E L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O18413 405 45839 Y23 G E G F R S Y Y I Q K I E E L
Honey Bee Apis mellifera XP_623053 405 45745 Y23 G E G F K P Y Y I T K I E E L
Nematode Worm Caenorhab. elegans O16368 443 49704 T56 A S K L P A V T P H A R C R L
Sea Urchin Strong. purpuratus XP_784151 401 45350 Y19 K D G I Q R Y Y I T K I E E L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9C5U3 419 47229 Y36 G E G L K Q Y Y L Q H I H E L
Baker's Yeast Sacchar. cerevisiae Q01939 405 45253 F23 E S G I K P Y F E Q K I Q E T
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.7 84.9 N.A. N.A. 44.7 42.7 N.A. N.A. 42 84.8 98 N.A. 91.8 91.6 41.5 89.9
Protein Similarity: 100 98.7 84.9 N.A. N.A. 62.3 61.1 N.A. N.A. 60.2 86.1 99 N.A. 95.5 95.8 62 96.3
P-Site Identity: 100 100 100 N.A. N.A. 0 20 N.A. N.A. 20 86.6 100 N.A. 66.6 60 20 53.3
P-Site Similarity: 100 100 100 N.A. N.A. 20 46.6 N.A. N.A. 46.6 100 100 N.A. 73.3 80 20 86.6
Percent
Protein Identity: N.A. N.A. N.A. 79.7 73.8 N.A.
Protein Similarity: N.A. N.A. N.A. 88.5 86.2 N.A.
P-Site Identity: N.A. N.A. N.A. 66.6 40 N.A.
P-Site Similarity: N.A. N.A. N.A. 73.3 66.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 15 0 0 0 0 8 0 0 0 0 8 0 0 0 0 % A
% Cys: 0 15 0 0 0 0 0 0 0 0 0 0 8 0 0 % C
% Asp: 0 8 0 0 0 0 0 0 0 0 0 0 0 22 0 % D
% Glu: 8 22 0 0 0 0 0 0 8 15 0 0 58 65 0 % E
% Phe: 0 0 0 15 0 0 0 8 0 0 0 0 0 0 0 % F
% Gly: 58 0 72 0 0 0 8 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 8 8 0 8 0 0 % H
% Ile: 0 0 0 15 0 0 0 0 22 0 0 86 0 0 8 % I
% Lys: 8 0 8 8 36 0 0 15 0 0 65 0 15 0 0 % K
% Leu: 0 8 8 65 0 15 15 0 58 0 0 0 0 0 72 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 8 15 0 0 8 0 0 0 0 0 0 % P
% Gln: 15 0 0 0 8 43 0 8 0 22 0 0 8 8 0 % Q
% Arg: 0 0 15 0 43 8 0 0 0 0 15 8 8 8 0 % R
% Ser: 0 43 0 0 0 8 0 0 8 36 0 8 0 0 0 % S
% Thr: 0 8 0 0 8 0 0 8 0 22 0 0 0 0 8 % T
% Val: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 72 65 0 0 8 0 0 0 15 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _